SPIRITUS: (12) A Monthly update from the Respiratory Technology team at the WIMR - end of year report and one year anniversary.
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This is our December update of news from the Respitech group at the WIMR.

The Respiratory Technology Team at the Woolcock Institute of Medical Research celebrate their first year of operation. The group has achieved a lot in the past 12 months. We have grown since January and  have had 22 research personal come through our doors. We have published 28 peer reviewed articles, sourced funding for a number of projects and have established wider initiatives within the community. To highlight some of the achievements over the past year the group has prepared an annual report outlining some of the initiatives and key performance outcomes. The report that can be downloaded here. Importantly, the group has partaken in a number of social events including, cook-ups, the famous hot pot adventure, all-important pub trips and a harbour cruise. To learn more about the social side of RespiTech you can always like us on Facebook  - www.facebook.com/RespiTech

In December, members of our group travelled to Edinburgh to participate at the Drug Delivery to the Lungs Conference, DDL24. Jesslynn Ooi, John Chan and Judy Loo were nominated to speak at the prestigious Pat Burnell New investigator award session. Prior to DDL, the group participated in the first ECR2STAR workshop in London. The conference was a great success and the team will be involved in developing new and and exciting early career programs in the coming year.
John Chan received a series of awards this month, including the Royal Society of NSW scholarship and best speaker at the AFPS conference in Korea. Meanwhile, YY (Hui Xin Ong) was awarded her PhD at The University of Sydney. YY was awarded an European Respiratory Society Postdoctoral fellowship and will move to the UK in early 2014 to commence a clinical focussed research project with Prof Joy Conway’s group in the area of medical imaging.

RespiTech 2013 Report.

RespiTech 2013 Report.

Also of note this month, the group announced the ISAM/Woolcock 2014 Joint Conference and workshop to be hosted in Sydney in September. The theme of the conference and further details will be announced in January via the Woolcock and ISAM websites.

Lastly, we would like to congratulate members of the group for publishing 4 peer reviewed articles this month. John published a review with Daniela entitled ‘An update on the use of rifapentine for tuberculosis therapy’ in Expert Opinion on Drug Delivery. Mehra was the first author on a publication in Pharmaceutical Research entitled ‘In vitro cell integrated impactor deposition methodology for the study of aerodynamically relevant size fractions from commercial pressurised metered dose inhalers’. This article describes the establishment and validation of a modified Anderson Cascade impactor for study drug transport across lung epithelia. Jesslynn published two articles as first author.  Firstly, she published an education article entitled ‘Graphing software for medical writers in the Journal of Medical Writing. Secondly, she published an article in Pharmaceutical Research entitled ‘Isothermal Calorimetry: A predictive tool to model drug-propellant interactions in pressurized metered dose systems’. This later article focusses on realtime monitoring of phase transitions in pMDI systems.

The group has come a long way in 2013 and we thank all our supporters and followers. We wish everyone a prosperous 2014 and look forward to the year ahead.

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Respiratory Technology @ the WIMR Congratulations Graduating Student
YY, Michele, Mariateresa & Eric

YY, Michele, Mariateresa & Eric

Hui Xin Ong (YY) was awarded the degree Doctor of Philosophy by the University of Sydney in an official graduation ceremony. YY started her PhD in 2010 in the Faculty of Pharmacy under the supervision of Paul Young, Daniela Traini (WIMR) and Mary Bebawy (UTS). YY submitted her thesis, entitled 'TRANSPORT MECHANISMS OF INHALED CIPROFLOXACIN FORMULATIONS ACROSS CALU-3 LUNG EPITHELIA' within 3 years of commencing. Dr YY has been employed at the Woolcock Institute of Medical Research (WIMR) since March 2013 as a Postdoctorate Researcher in Respiratory Technology. YY  has made an outstanding achievement as an early career researcher and has already published 7 research articles in high impact journals within her field, as well as a number of peer reviewed full conference papers. YY has been awarded a European Respiratory Society Postdoctoral fellowship and will move to the UK in early 2014 to commence a clinical focussed research project with Prof Joy Conway’s group in the area of medical imaging.

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John Chan awarded best ECR talk at ECR2STAR 2013
John Chan receiving award from Dr David Lewis (Chiesi UK Ltd) with PhD supervisor A/Prof Daniela Traini

John Chan receiving award from Dr David Lewis (Chiesi UK Ltd) with PhD supervisor A/Prof Daniela Traini

John Chan was awarded best early career speaker during the ECR2STAR workshop and conference held in London this December. 60 early career researchers and established academics attended the conference to discuss opportunities and hints and tips for becoming a leader in academia and industry. In the afternoon 11 ECRs showcased their work. John’s received an award for his talk on targeting TB and received a certificate and £200.

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Royal Society of NSW award for John Chan
John Chan

John Chan

John Chan has been awarded a scholarship from the Royal Society  of NSW acknowledging his outstanding achievements as a young researcher. John, a postgraduate researcher in the Respiratory Technology group at the Woolcock Institute and Sydney Medical School, will receive the award and give a presentation at the society's general meeting and a paper for the Society's Journal in the new year. The award consists of a certificate acknowledging achievement, a $500 prize and a complimentary year of membership to the Society. 

You can learn more about the society and award here

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Woolcock & ISAM to host 2014 Joint Conference & Workshop in Sydney
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ISAM-Woolcock Institute Joint Conference on “Translating Advances in Understanding Lung Disease into Innovative Inhaled Therapeutics”The Woolcock Institute in Sydney, Australia is leading advances in understanding the mechanisms of lung diseases at the cellular level; it also has a long history of treating patients and improving their compliance through education and training on use of inhalers.  In between these two ends of the research spectrum is the effort to translate the advances in basic science into innovative therapeutic products that will make a difference in these patients’ lives.  To this end, ISAM and its members at the Woolcock Institute are planning a joint conference focused on “Translating Advances in Understanding Lung Disease into Innovative Inhaled Therapeutics” scheduled for September 25-26, 2014 in Sydney, Australia.  Please check the ISAM  www.isam.org and Woolcock www.woolcock.org.au websites regularly for more updates.

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SPIRITUS: (11) A Monthly update from the Respiratory Technology team at the WIMR

This is our November update of news from the Respitech group at the WIMR.

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In November, the RespiTech group has participated in a number of events. Firstly, we were involved in the Woolcock ‘Think Tank’, a two day conference that highlights the institute’s research strengths and identifies strategic directions for future projects and collaborations. Judy Loo gave an excellent presentation on modified intubation tubes for reducing pneumonia infection in ICU patients and Wing-Hin participated in the Woolcock’s ECR Translational Research Grant, pitching a novel lung cancer therapy. Also, YY won a bottle of bubbly for being the most enthusiastic ECR participant!

The team participated in the annual Melbourne Cup celebrations at the Institute. Meanwhile, Dany Traveled to Italy to conduct a series lectures as Visiting Professor at the University of Ferrara, while Paul went to AAPS in San Antonio USA to establish a series of new collaborations.

Later in the month, the team participated in the Chancellor’s reception at the Woolcock to celebrate a series of Centres of Excellence, a Corporative Research Centre, and the Woolcock Advanced Microscopy Suite. Paul spoke about the new microscopy facilities which are now operational.

As usual we welcome and say goodbye to RespiTech members. This month we say goodbye to Amitabh Prakesh and Ningyi Xu. Amitabh completed his Hons thesis on cilia beat function and was awarded his degree at the end of November. Ningyi completed her Masters degree with the team in the area of pressurised metered dose inhaler droplet drying kinetics. We wish both all the best in their future career. 

We would like to congratulate Eric (Bing Zhu) for being awarded his PhD from the University of Sydney. Erics’s thesis is entitled “The influence of formulation variables on particles generated from solution based pressurised metered dose inhalers”. Eric will continue working with the group as a postdoctoral scientist within the field of aerosol generation.

We would also like to congratulate Alaa Tulbah and Yang Chen for giving excellent PhD presentations at the Woolcock’s Friday morning seminars.

Lastly, we would like to congratulate Yang and Eric for publishing two papers this month. Yang was the first author on a publication in ‘Pharmaceutical Research’ entitled ‘The influence of actuator materials and nozzle designs on electrostatic charge of pressurised metered dose inhaler (pMDI) formulations’ while Eric was the first author on a paper in ‘Colloids and Surfaces A’ entitled ‘The solid-state and morphological characteristics of particles generated from solution-based metered dose inhalers: influence of ethanol concentration and intrinsic drug properties’. Both these publications focus on one of areas of interest of the group- pMDI technology, and the study of particle properties after aerosol generation.


Woolcock Think Tank 2013

Alaa and Yang give woodcock seminar

Chancellors reception

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SPIRITUS: (10) A Monthly update from the Respiratory Technology team at the WIMR
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This is our October update of news from the Respitech group at the WIMR.

October has been a hectic yet productive month for the Respitech group. Firstly the team hosted the Drug Delivery Australia Conference (DDA 2013) at the Woolcock Level 5 conference venue. 100 national and international delegates participated and we had keynote speakers Igor Gonda (Aradigm) and Ian Tucker (current president of the CRS) give insightful talks on the future of drug development and delivery. The conference ran over 2 days and covered a range of topics including respiratory drug delivery, cancer targeting and novel drug delivery vehicles. There were a number of student prizes, great food, a highly popular ice-cream cart and a cruise on the harbour. Thanks to the whole team for all the effort they have put in to make this a success!

DDA2013 Delegates

DDA2013 Delegates

Meanwhile, the ECR2STAR program is picking up pace. We are already approaching capacity for our first workshop in London and have finalised the academic and industrial speakers. The web-site has been visited by 2000 people and we have contributors from around the globe participating with articles and comments via Facebook and Linkedin. If you are a early career research and want to learn more visit ecr2star.org.

Back at the Institute, members of the group have been busy working to develop the Woolcock’s new profile and have successfully launched the new woolcock.org.au web portal. This was completed in time for the Governor of New South Wales reception for the Institute, held at Government house in Sydney which Paul attended on behalf of the Respiratory Technology Group.

We would like to congratulate YY (Hui Xin Ong) for being awarded her PhD from the University of Sydney. YY’s thesis is entitled ‘Transport Mechanisms of Inhaled Ciprofloxacin Formulations Across Calu-3 Lung Epithelia’ YY will continue working with the group and spend next year applying the findings from her thesis to transport kinetics of drugs in humans, using scintigraphic techniques at Southampton Hospital in the UK.

Lastly, we would like to congratulate John Chan and Alessandro  Sadat for publishing two papers this month. John was the first author on a paper published in Pharmaceutical Research, focussing on novel inhaled anti-tuberculosis drugs while Alessandro ’s paper in Journal of Pharmacy and Pharmacology described a inhaled macrolide formulation designed to target bronchiectasis.

 

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SPIRITUS: (09) A Monthly update from the Respiratory Technology team at the WIMR

This is our September update of news with the RespiTech group at the WIMR

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September has been an exciting month with the establishment of a series of new initiatives.

Firstly, we have launched a new initiative for young researchers: www.ecr2star.org. Early career researcher to research star (ECR2STAR) is a global initiative to encourage early career researchers (PhD, PostDocs and early career academics and industry researchers) to become the next leaders in their field. 

We have established a website that will be a repository of useful information, news, links and opportunities for ECRs. Additionally, the group has announced the first free ECR2STAR workshop, to be hosted in London this December as part of a collaborative project between University College London, University of Sydney and the Woolcock Institute of Medical Research. For more information follow the link www.ecr2star.org

Secondly, we launched SPAM (Strategic Promotion Advice and Mentoring). Daniela Traini at the WIRM together with colleagues Penny Oxford and Fiona White both from the Faculty of Science, have organized the very first ‘Promotions myths and legends workshop’. Fifteen Level D women in Science, Vet Science, Agriculture and Environment and Medicine Interested in applying for Level E in 2014 or 2015 attended.  The next meeting will be held at the Woolcock Institute on Tuesday the 22nd of October 1-2.30pm. Please send Daniela an email if you are interested in attending. 

As always, we welcome members to the Respitech team. This month we have two new members, Gianluca Lauretani and Mariateresa Stigliani. Gianluca is a visiting student from The University of Ferrara (Italy) and will work on combination therapies for targeting muco-hypersecretion and bacterial infection in the lung, while Mariateresa is a PhD student from Salerno (Italy) who will be studying drug transport phenomena across lung epithelia. Welcome to both. 

We would also like to congratulate Gianluca on securing one of 8 scholarships valued at Euro 2500 (>$3500) from the Atlante-Rotary Club in Ferrara to support international mobility. Well done!

Finally, the DDA2013 program for the October conference has now been finalised and the event is shaping up to be a success. We are projected to have over 100 delegates with world-class speakers and abstracts. More on this in next month newsletter.

 

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RespiTech Members launch a Free ECR2STAR workshop in London this December
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Members of the RespiTech group are please to announce a workshop for young and early career researchers in the biomedical and drug delivery fields. The workshop will be held in collaboration with UCL members and will focus on career development. The workshop will also give ECRs the opportunity to speak about their research.

The ECR2STAR team is pleased to announce our first workshop for early career researchers in London this December. If you are a PhD student or early career researcher (ECR) postdoctoral scientist working in the area of drug delivery and biomedical science this workshop is for you!

 Learn how to get the most out of your research career

 Listen and interact with leaders in both academia and industry

Present your data to other ECRs and stand the chance to win £200

The conference will be held on the 9th December at Senate House in London (UK) and is brought to you by: University College London, The University of Sydney and The Woolcock Institute of Medical Research.  

Most importantly, this workshop is free!

You can register online at http://ecr2star.org/2013-conference/

 

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Final Program for DDA2013 in Sydney Announced
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Click image for final program pdf

The final program for DDA2013 was announced today. Members of the RespiTech group are please to be hosting this successful drug delivery conference series at the Woolcock Institute of Medical Resaerch on the 24th and 25th October 2013. We look forward to seeing you there!

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