Advances in the use of cell penetrating peptides for respiratory drug delivery

Gomes Dos Reis, L., Lee, WH., Svolos, M., Moir, L., Jabe, R., Winhab, N., Young, PM., Traini, D. (2020) 

Respiratory diseases are leading causes of death in the world, still inhalation therapies are the largest fail in drug development. There is an evident need to develop new therapies. Biomolecules represent apotential therapeutic agent in this regard, however their translation to the clinic is hindered by the lack of tools to efficiently deliver molecules. Cell penetrating peptides (CPPs) have arisen as apotential strategy for intracellular delivery that could theoretically enable the translation of new therapies.

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